Preface Acknowledgements Dedication PartⅠ:Processes of Metabolism and Nutrition 1.Overview of Metabolism Useful definitions Basic principles of bioenergetics 2.Carbohydrate and Energy Metabolism Glycolysis and its regulation Central role of acetyl CoA Tricarboxylic acid cycle (TCA Cycle) Generation of ATP Glycogen metabolism Role of 2,3-bisphosphoglycerate Fructose,galactose,ethanol,and sorbitol 3.Production of NADPH Pentose phosphate pathway and the pyruvatemalate cycle The roles of NADPH 4.Lipid Metabolism Lipid biosynthesis Lipid breakdown Cholesterol metabolism Transport of lipids The ketone bodies 5.Protein Metabolism Biosynthesis of the non-essential amino acids Protein breakdown and the disposal of nitrogen Gluconeogenesis and the metabolism of amino acids to glucose and fat Amino acid metabolism in individual tissues 6.Purines,Pyrimidines,and Haem One-carbon pool Purine metabolism Pyrimidine metabolism Haem metabolism 7.Metabolic Integration Glucose homeostasis 8.Nutrition Basic principles of human nutrition Energy balance Protein nutrition Vitamins Minerals PartⅡ:Clinical Assessment 9.Taking a History Things to remember when taking a history Common presenting complaints 10.Examination of the Patient General inspection Limbs Head and neck Thorax The abdomen 11.Further Investigations Routine investigations Assessment of nutritional status PartⅢ:Basic Pathology 12.Important Metabolic Disorders Disorders of glucose and energy metabolism Disorders of lipid metabolism Disorders of amino acid metabolism Disorders of purine pyrimidine metabolism Disorders of haem metabolism 13.Important Nutritional Disorders Disorders of protein nutrition and energy balance The fat-soluble vitamins:deficiency and excess The water-soluble vitamins:effects of deficiency Disorders of mineral nutrition PartⅣ:Self-assessment Multiple-choice Questions Short-answer Questions Essay Questions MCQ Answers SAQ Answers Index
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