Preface Ackowledgements Dedication PartⅠ:Development,Structure and Function 1.Overview of the Immune,Blood and Lymphatic Systems The players-an overview of the cell lines 2.Organization of the Lymphoid System Primary lymphoid organs Secondary lymphoid organs 3.Concepts of lmmunity Innate and adaptive immunity The innate immune system Recognition molecules:The B cell Recognition molecules:The T cell Generation of antigen receptor diversity Humoral immunity Cell-mediated immunity The complement system 4.The lmmune System in Disease Response to tissue damage Hypersensitivity mechanisms Immune response to pathogens Autoimmunity and immune disease Immunization Transplantation 5.Red Blood Cells and Haemoglobin Structure and function of erythrocytes Erythropoiesis Lron and haem metabolism Haemoglobin The red cell cytoskeleton Metabolism of red cells 6.Haemostasis Platelets and blood coagulation The coagulation cascade 7.Serum Proteins Normal serum proteins Acute phase proteins 8.Serology and Blood Transfusion Red cell antigens Blood transfusion PartⅡ:Clinical Assessment 9.Taking a History Structure of a history Common presenting complaints 10.Clinical Examination 11.Further Investigations Haematological investigations Investigation of immune Function PartⅢ:Basic Pathology 12.Disorders of Immunity Autoimmune disease Diseases of immune deficiency Amyloidosis 13.Disorders of White Cells,Lymph Nodes and the Spleen Leukopenia Reactive proliferation of white cells Neoplastic proliferation of white cells Disorders of the spleen 14.Disorders of Red Cells Anaemia due to blood loss Anaemia due to red cell destruction(haemolytic anaemias) Anaemia due to impaired red cell production 15.Disorders of Red Cells Bleeding disorders:platelets Bleeding disorders:clotting factor abnormalities Thrombosis PartⅣ:Self-assessment Multiple-choice questions Short-answer questions Essay questions MCQ answers SAQ answers Index