中文摘要 药理学 MAPK-specific tyrosine phosphatases: new targets for drug discovery? Alastair J. Barr and Stefan Knapp MAPK特异性酪氨酸磷酸酶：药物发现的新靶点? Ca2+ signalling and pancreatitis: effects of alcohol, bile and coffee Ole H. Petersen and Robert Sutton Ca2+信号和胰腺炎：酒精、胆汁和咖啡的作用 The function of breast cancer resistance protein in epithelial barriers, stem cells and milk secretion of drugs and xenotoxins Antonius E. van Herwaarden and Alfred H. Schinkel 乳腺癌耐药蛋白在上皮屏障、干细胞以及乳汁分泌药物和外毒素中的作用 Use of P-glycoprotein and BCRP inhibitors to improve oral bioavailability and CNS penetration of anticancer drugs Pauline Breedveld, Jos H. Beijnen and Jan H.M. Schellens 利用P-糖蛋白和BCRP抑制剂改善抗癌药物的口服生物利用度和中枢神经系统渗透性 The expression and function of chemokines involved in CNS inflammation Eroboghene E. Ubogu, Michael B. Cossoy and Richard M. Ransohoff 中枢神经系统炎症中趋化因子的表达和功能 The role of the endoplasmic reticulum Ca2+ store in the plasticity of central neurons Scott Bardo, Michele G. Cavazzini and Nigel Emptage 内质网钙池在中枢神经元可塑性中的作用 Novel class of pain drugs based on antagonism of NGF Franz F. Hefti, Arnon Rosenthal, Patricia A. Walicke, Sean Wyatt, German Vergara, David L. Shelton and Alun M. Davies 拮抗神经生长因子的新一类镇痛药 Behavioural pharmacology: 40+ years of progress, with a focus on glutamate receptors and cognition Trevor W. Robbins and Emily R. Murphy 行为药理学：有关谷氨酸受体与认知40余年研究进展 The quantitative analysis of drug-receptor interactions: a short history David Colquhoun 药物-受体相互作用的定量分析：一段简短的历史 Smooth muscle research: from Edith Bülbring onwards Alison F. Brading 始于Edith Bülbring的平滑肌研究 Historical review: ATP as a neurotransmitter Geoffrey Burnstock 关于神经递质ATP的历史性回顾 Endogenous inverse agonists and constitutive receptor activity in the melanocortin system Roger A.H. Adan 内源性反向激动剂调节黑素细胞皮质激素固有受体活性 New light on multidrug binding by an ATP-binding-cassette transporter Richard A.Shilling,Henrietta Venter,Saroj Velamakanni, Akanksha Bapna, Barbara Woebking, Sanjay Shahi and Hendrik W.van Veen 关于ATP结合盒转运蛋白介导的多药结合新见解 P2 receptors and cancer Nicholas White and Geoffrey Burnstock P2受体与肿瘤 Techniques: New pharmacological perspectives for the leptin receptor Frank Peelman, Cyril Couturier, Julie Dam, Lennart Zabeau, Jan Tavernier and Ralf Jockers 技术：瘦素受体新的药理学前景 Targets in ALS: designing multidrug therapies Maria Teresa Carrì, Giuliano Grignaschi and Caterina Bendotti 设计多药治疗肌萎缩性脊髓侧索硬化症的靶标 Angiogenesis: from plants to blood vessels Tai-Ping Fan, Ju-Ching Yeh, Kar Wah Leung, Patrick Y.K. Yue and Ricky N.S. Wong 血管生成：从药用植物到血管 Neurotransmitter transporters: molecular function of important drug targets Ulrik Gether, Peter H. Andersen, Orla M. Larsson and Arne Schousboe 神经递质转运蛋白：重要的药物作用靶标的分子功能 Higher-order organization and regulation of adenylyl cyclases Dermot M.F. Cooper and Andrew J. Crossthwaite 高级构造与腺苷酸环化酶的调控 Transport of glutathione and glutathione conjugates by MRP1 Susan P.C. Cole and Roger G. Deeley MRPI介导谷胱苷肽及谷胱苷肽偶联物的转运 Analgesic strategies beyond the inhibition of cyclooxygenases Hanns Ulrich Zeilhofer and Kay Brune 环氧合酶抑制途径以外的止痛策略 Allosteric agonists of 7TM receptors: expanding the pharmacological toolbox Christopher J. Langmead and Arthur Christopoulos 七次跨膜受体的异构激动剂：更广泛的药理学应用 Chemokine receptors as therapeutic targets in chronic obstructive pulmonary disease Louise E. Donnelly and Peter J. Barnes 趋化因子受体作为慢性阻塞性肺部疾病的治疗靶标 How important is protein kinase C in μ-opioid receptor desensitization and morphine tolerance? Chris P. Bailey, Forrest L. Smith, Eamonn Kelly, William L. Dewey and Graeme Henderson 蛋白激酶C在μ-阿片受体脱敏和吗啡耐受中如何发挥重要作用? Emerging cancer therapeutic opportunities target DNA-repair systems Jian Ding, Ze-Hong Miao, Ling-Hua Meng and Mei-Yu Geng 靶向DNA修复系统展露出抗肿瘤治疗新机会
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