COLOR PLATES 1-8 follow Contents. SECTION I PHARMACOLOGIC INTERVENTION 1 Role of Platelet Inhibitor Agents in Coronary Artery Disease 3 Jeffrey Lefkovits Eric J. Topol 2 Anticoagulants and Their Use in Acute Coronary Syndromes 23 David]. Moliterno 3 Effects of Beta Blockers, Calcium Channel Blockers, Nitrates, and Magnesium in Acute Myocardial Infarction and Unstable Angina Pectoris 33 Peter H. Held Koon K, Teo Salim Yusuf 4 Angiotensin-Converting Enzyme Inhibition 67 Marc A. Pfeffer 5 Thrombolytic Intervention 78 EricJ. Topol 6 Hypolipidemic intervention and Plaque Stabilization 111 Robert A. Vogel SECTION n CORONARY AND PERIPHERAL INTERVENTION: KEY APPLICATIONS 12- Coronary and Peripheral Angioplasty: Historical Perspective 127 Richard K, Myler Elective Coronary Angioplasty: Technique and Complications 147 Stephen G. Ellis Abrupt Vessel Closure 163 A. Michael Lincoff Eric J. To{(l Complex and Multivessel Treatment 188 David R. Holmes, Jr. - Peter B. Berber i Efficacy of Percutaneous Transluminal Coronary Angioplasty: Randomized Trials of Myocardial Revascularization 209 Daniel J. Diver Bernard J. Gersh Percutaneous Coronary Intervention for lJ ilstable Angina 238 Pim J. de Feyter Periprocedural Myocardial Infarction 236 Keith H. Benzuly Charles J. Davidson Catheter-Based Reperfusion for Acute Myocardial Infarction 263 EricJ, Topol 5 (chronic Total Occlusion 280 Bernhurd Meter 6 Percutaneous Intervention in Patients with Prior Coronary Bypass Surgery 297 John S. Douglas, Jr. 7 Ostial and Bifurcation Lesions 317 Patrick L Whitlow Long Lesions and Diffuse Disease 333 Masakiyo Nobuyoshi Hiroyoshi Yokoi Craig R. Narins Restenosis: Involvement of Growth Factors and Cytokines 346 Peter Libby Elazer Edelman Animal Models of Human Coronary Restenosis 338 Robert S. Schivartz Restenosis: The Clinical Issues 379 Julie M. Miller E. Magnus Ohman David]. Moliterno Robert M. Califf Approach to Restenotic Lesions 417 Craig R. Narins Eric J. Topol Site-Specific Therapy for the Prevention of Restenosis 433 David W. M. Muller b The Pathology of Various Mechanical Interventional Procedures and Devices 447 Bruce E Waller Peter G. Anderson Surgical Standby for Percutaneous Transluminal Coronary Angioplasty 466 Bernhard Meier Angioplasty and Interventional Vascular Procedures in the Peripheral, Renal, Visceral, and Extracranial Circulation 473 Mark H. Wholey Arthur J. Nussbaum Michael Wholey 7 Coronary Atherectomy: Directional and Extraction Techniques 301 Robert D. Safian Rotational Atherectomy 323 Michel E. Bertrand Eric Van Belle Stents: The Menu 333 Michael B. Kutryk Patrick W Serruys Stent Anticoagulation and Technique 387 Franz-Josef Neumann Albert Schornig Stents: Indications and Limitations 602 lk-KyungJang Sheldon Goldberg Laser 613 On Topaz Ultrasound Angioplasty 634 Roberta Siegel Wolfgang Steffen David C. Cumberland A Radiation 630 Judah Weinberger Percutaneous Myocardial Revascularization and Angiogenesis 664 Craig R. Norms EricJ. Topol 16 Genetic Therapies for Cardiovascular Disease 684 Elizabeth G. Nabel GaryJ. Nabel 17 Percutaneous Vascular Hemostasis Devices for Arterial Sealing After Interventional Procedures 693 Timothy A. Sanborn William G. Kussmaul III Tomoaki Hinohara ECTION m EVALUATION OF CORONARY NTERVENTIONAL TECHNIQUES 701 18 Interventional Approaches to the Introduction of Genetic Material into the Cardiovascular System 703 David A. Dichek 19 Qualitative and Quantitative Angiography 723 Alexandra J. Lansky Jeffrey J. Popma 20 Intracoronary Doppler and Pressure Monitoring 748 Stephane G. Carlier Carlo Di Mario Morton J. Kern Patrick W Serruys 21 Coronary Angioscopy 783 Christopher J. White Stephen R. Ramee 22 Intravascular Ultrasound 801 Paul G, Yock Peter J. Fitzgerald Yasuhiro Hondo ECTION IV ALVULOPLASTY, CONGENITAL AND PERICARDIAL HEART DISEASE 819 23 Mitral Valvuloplasty 821 Alee Vahanian Bernard lung Bertrand Cormier44 Advances in Percutaneous Aortic and Mitral Valvuloplasty 839 Alain Cribier Brice Letac 45 Balloon Valvuloplasly and Stenting for Congenital Heart Disease 830 Robert H. Beekman III Thomas R. Lloyd Percutaneous Balloon Pericardiotomy for Patients with Pericardial Effusion and Tamponade 869 Andrew A. Ziskind lgor E Palacios Percutaneous Transluminal Septal Myocardial Ablation for Hypertrophic Obstructive Cardiomyopathy 878 Hubert Seggewiss Lothar Faber Arvinder S. Kurbaan Ulrich Sigwart SECTION V OUTCOME EFFECTIVENESS OF INTERVENTIONAL CARDIOLOGY 8 48 Medical Economics for Interventional Cardiology 889 Daniel B. Mark 49 Quality of Care in Interventional Cardiology 9 EricJ. Topol 50 Training, Credentialing, and Guidelines 921 Thomas J. Ryan 51 Medicolegal Issues 929 M. Lee Cheney Daniel B. Mark Index 943