目 录 序言 第一篇血红蛋白A2现象的发现和研究一证明红细胞内血红蛋白A2与Ai之间的相互作用 1 第一篇前言 2 第一章血红蛋白A2现象一I . A2现象的发现及其初步应用 6 第二章血红蛋白A2现象一II. a链异常血红蛋白的A2现象及其意义 12 第三章血红蛋白A2现象一III. S链异常血红蛋白的A2现象及其意义 16 第四章血红蛋白A2现象发生机制的研究——I .红细胞外血红蛋白A与血红蛋白A2之间的相互作用 19 第五章血红蛋白A2现象发生机制的研究一II. “红细胞HbA/’为HbA2与HbA的结合产物 24 第六章血红蛋白A2现象与红细胞膜关系的研究——I .血红蛋白A2现象与溶血的关系 28 第七章血红蛋白A2现象与红细胞膜关系的研究一II.红细胞外血红蛋白与磷脂间的相互作用 32 第八章血红蛋白A2现象异常症(秦氏病) 39 第九章用电泳释放试验检测活体红细胞内血红蛋白之间的相互作用 43 第十章血红蛋白A2现象国外书中引用情况 53 第二篇血红蛋白之间交叉互作的发现和研究 65 第二篇前言 66 第十一章淀粉琼脂糖混合凝胶电泳 70 第十二章淀琼胶交叉互作电泳 74 第十三章血红蛋白交叉互作的结构基础 77 第十四章红细胞外HbA2与HbA之间的相互作用 80 第十五章 电泳释放试验检测活体红细胞内血红蛋白的相互作用 85 第十六章血红蛋白F与血红蛋白A2之间的交叉互作 95 第十七章血红蛋白A3与血红蛋白A2之间没有交叉互作 98 第十八章活体大鼠红细胞内血红蛋白之间的交叉互作一一大鼠红细胞结晶的可能机制 101 第十九章脊椎动物血红蛋白的分子进化一一交叉电泳在血红蛋白研究中的应用106 第二十章几种鱼类血红蛋白不与人血红蛋白相互作用及其进化意义 116 第二十一章美国锦龟血红蛋白与人血红蛋白相互作用的生物信息学和计算机模拟研究 121 第二十二章计算机模拟法分析鸡血红蛋白与溴酚蓝特异性互作的结构基础 128 第二十三章生物信息学方法推测脊椎动物血红蛋白相互作用机制 136 第二十四章血红蛋白的聚丙烯酰胺凝胶交叉电泳 143 第三篇血红蛋白再释放现象的发现和研究 149 第三篇前言 150 第二十五章血红蛋白释放试验与轻型p-地中海贫血 156 第二十六章不连续通电的红细胞电泳一一种新的血红蛋白释放试验 160 第二十七章普通外科患者血红蛋白释放试验的比较研究 165 第二十八章血糖浓度和血红蛋白释放试验的比较研究 170 第二十九章尿毒症患者低渗血红蛋白释放试验的初步结果 173 第三十章血红蛋白释放试验与血液流变学检测结果相关性的研究 177 第三十一章肝硬化患者血红蛋白释放试验明显异常 180 第三十二章人红细胞电泳中再释放蛋白质的分子互作 186 第三十三章剖宫产前后血红蛋白释放试验的连续观察 192 第三十四章肝内胆管癌与血红蛋白释放试验 196 第三十五章血红蛋白释放试验鉴别黄疸类型的初步研究 200 第三十六章中药穿心莲和当归对小鼠红细胞血红蛋白再释放的影响 204 第三十七章梅花鹿镰状红细胞内血红蛋白的电泳释放 209 第三十八章遗传性球形红细胞增多症患者红细胞内快泳血红蛋白缺失? 214 第三十九章慢阻肺患者红细胞内血红蛋白的电泳再释放一一例报告 221 第四十章球形红细胞与靶形红细胞电泳释放血红蛋白明显不同 224 第四^^一章缺氧对小鼠红细胞再释放血红蛋白的影响 230 第四十二章血红蛋白电泳再释放研究国外引用情况 232 附录1血红蛋白电泳释放实验专用名词注释 234 附录2 电泳图画 245 CONTENTS Preface Foreword PART I Discovery and Research into “HbA2 Phenomenon” ~Proved Interaction BetweenHbA2 and HbA1 Inside of RBC 1 PART I Foreword 4 Chapter 1 Hemoglobin A2 phenomenon— I . Discovery and preliminary application ofthis phenomenon 6 Chapter 2 Hemoglobin A2 Phenomenon—II. HbA2 Phenomenon of a-ChainVariant and Its Significance 12 Chapter 3 The Hemoglobin A2 Phenomenon—III. HbA2 Phenomenon of 8-ChainVariant and Its Significance 16 Chapter 4 Mechanism of Hemoglobin A2 Phenomenon— I . Extra-cellular InteractionBetween HbA2 and HbA 19 Chapter 5 Mechanism of Hemoglobin A2 Phenomenon—II. “Erythrocyte HbA2” Isa Binding Product of HbA2 and HbA 24 Chapter 6 Studies On The Relation Between “HbA2 Phenomenon” and ErythrocyteMembrane— I . The Relation Between HBA2 Phenomenon and Hemolysis ofErythrocyte 28 Chapter 7 Studies on The Relation Between “HbA2 Phenomenon” and Erythrocyte Membrane—II Interaction of Hemoglobin with Phospholipid Outside of Erythrocyte 32 Chapter 8 Hemoglobin A2 Phenomenon Abnormality (Chin’s Disease) 39 Chapter 9 Interactions of hemoglobin in live red blood cells measured by the electrophoresisrelease test 43 Chapter 10 Cited by book published out side of China: HbA2 Phenomenon 53 PART II Discovery and Research into “Cross interaction between hemoglobins” 65 PARTI Foreword 68 Chapter 11 Starch-agarose mixed gel electrophoresis 70 Chapter 12 Starch-agarose mixed gel cross interaction electrophoresis 74 Chapter 13 Structural basis of hemoglobin cross interaction Monographs 77 Chapter 14 Extra-cellular Interaction between HbA2 and HbA 80 Chapter 15 Interactions of hemoglobin in live red blood cells measured by the electrophoresis release test 85 Chapter 16 Cross interaction between HbF and HbA2 95 Chapter 17 No cross interaction between HbA3 and HbA2 98 Chapter 18 Cross interaction between hemoglobins within the living red blood cells fromrat— The possible mechanism of crystallization of rat erythrocyte 101 Chapter 19 Molecular evolution of vertebrate hemoglobin—Application of crosselectrophoresis in hemoglobin study 106 Chapter 20 Fish Hb’s Failing to Interact with Human Hb and Its Evolutionary Significance 116 Chapter 21 Bioin formatic and Molecular Modeling Analysis on the Interaction ofWesten Pained Turtle Hemoglobin and Human Hemoglobin 121 Chapter 22 Structural basis for the specific interaction of chicken hemoglobin withbromophenol blue: a computational analysis 128 Chapter 23 Extrapolation of interactive mechanism of hemoglobin in vertebrates bymethods of biological information science 136 Chapter 24 Polyacrylamide gel cross electrophoresis of hemoglobin 143 PART I Discovery and Research into “Hb Re-release Phenomenon” 149 PART I Foreword 153 Chapter 25 Hemoglobin Release Test and P - Thalassem in Trait 156 Chapter 26 RBC electrophoresis with discontinuous power supply a newly establishedhemoglobin release test 160 Chapter 27 The Comparative Study On Hemoglobin Release Test Between DifferentGeneral Surgical Patients 165 Chapter 28 Comparative Study on the Blood Glucose Concentration and HemoglobinRelease Test 170 Chapter 29 A preliminary study on hypotonic hemoglobin release test in patients withuremia 173 Chapter 30 Study on the correlation between results of hemoglobin release test andhemorheology 177 Chapter 31 Particularly abnormal result of hemoglobin release test in blood samplesof patients with liver cirrhosis 180 Chapter 32 Molecular interactions of re-released proteins in electrophoresis ofhuman erythrocytes 186 Chapter 33 Study on the significance of continuous observation on hemoglobin releasetest before and after cesarean delivery 192 Chapter 34 Intrahepatic bile duct carcinoma and hemoglobin release test 196 Chapter 35 Preliminary research about identify jaundice type by Hemoglobin ReleaseTest 200 Chapter 36 The effect of Andrographis paniculata and Angelica sinensis on the hemoglobinrelease of mice blood cell 204 Chapter 37 Electrophoresis release of hemoglobin from Sika deer sickle red blood cells 209 Chapter 38 Absence of fast moving Hb in RBC of hereditary spherocytosis patient? 214 Chapter 39 Electriphoresis Re-release of Hemoglobin from Erythrocyte of COPD Patient 221 Chapter 40 Electrophoresis release of hemoglobin is distinctly different between spherocyteand target cell 224 Chapter 41 Anoxia effect on re-release of hemoglobin from mice erythrocyte 230 Chapter 42 Citation Our “re-release”study was cited by book published outside of Chinain page 232 Appedix I Notes of Experimental Term of Hemoglobin Release Electrophoresis 234 Appedix II Electrophoresis Picture 245
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